GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs2985684 | 1 | rs1957977 | chr14:50090603 | RPL36AL | chr14:50085407-50087349:- | 0.24 | 4.44 | 1.16E-5 | Carotid intima media thickness |
| BLCA | cis | rs1577917 | 1 | rs1962716 | chr6:86648436 | SNHG5 | chr6:86386726-86388451:- | -0.54 | -9.5 | 2.33E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs2243480 | 1 | rs1964692 | chr7:65454183 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.38 | 1.54E-5 | Diabetic kidney disease |
| BLCA | cis | rs1971762 | 1 | rs1971762 | chr12:54058238 | ATP5G2 | chr12:54058945-54070512:- | 0.22 | 4.86 | 1.71E-6 | Height |
| BLCA | cis | rs6547741 | 1 | rs1972669 | chr2:27767107 | C2orf16 | chr2:27799389-27805588:+ | 0.23 | 3.97 | 8.5E-5 | Oral cavity cancer |
| BLCA | cis | rs41266839 | 1 | rs1979 | chr6:26377591 | BTN3A2 | chr6:26365398-26378546:+ | -0.74 | -12.03 | 1.76E-28 | Schizophrenia |
| BLCA | cis | rs2243480 | 1 | rs1979823 | chr7:65704613 | CCT6P1 | chr7:65216092-65228661:+ | -0.33 | -4.52 | 8.25E-6 | Diabetic kidney disease |
| BLCA | cis | rs6918586 | 1 | rs198806 | chr6:26133616 | BTN3A2 | chr6:26365398-26378546:+ | 0.2 | 4.12 | 4.66E-5 | Schizophrenia |
| BLCA | cis | rs6918586 | 1 | rs198811 | chr6:26128446 | BTN3A2 | chr6:26365398-26378546:+ | -0.19 | -4.03 | 6.7E-5 | Schizophrenia |
| BLCA | cis | rs199347 | 1 | rs199347 | chr7:23293746 | GPNMB | chr7:23286316-23314728:+ | -0.25 | -4.26 | 2.6E-5 | Parkinson's disease |
| BLCA | cis | rs199347 | 1 | rs199348 | chr7:23293098 | GPNMB | chr7:23286316-23314728:+ | -0.23 | -3.83 | 0.000148 | Parkinson's disease |
| BLCA | cis | rs199347 | 1 | rs199351 | chr7:23300049 | GPNMB | chr7:23286316-23314728:+ | -0.25 | -4.1 | 4.99E-5 | Parkinson's disease |
| BLCA | cis | rs199347 | 1 | rs199357 | chr7:23288309 | GPNMB | chr7:23286316-23314728:+ | 0.24 | 4.02 | 6.96E-5 | Parkinson's disease |
| BLCA | cis | rs9815354 | 1 | rs1994157 | chr3:41897482 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.5 | 2.29E-19 | Diastolic blood pressure |
| BLCA | cis | rs1577917 | 1 | rs1995688 | chr6:86632319 | SNHG5 | chr6:86386726-86388451:- | -0.51 | -9.03 | 8.38E-18 | Response to antipsychotic treatment |